Vitamin B1 Deficient Animals and Poliomyelitis *

In previous experiments,2 an unsuccessful attempt was made to acclimate monkey cord virus to white rats, which had been made completely vitamin B1 deficient by feeding them a vitamin B1 free diet for 30 days prior to the start of the experiment. It was thought that our failure might have been due to the fact that we did not have the animals in a proper state or stage of deficiency; perhaps the animals might have been continued on the diet for too long a period. Further experiments were planned in which the vitamin B, intake was varied.